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Just one injection: what is known about the Sputnik Light coronavirus vaccine
Just one injection: what is known about the Sputnik Light coronavirus vaccine
Anonim

At the end of June 2021, Russians began to be vaccinated with the Sputnik Light vaccine. It was made by the same scientists from the Gamaleya Center who were responsible for the creation of Sputnik V - the most widespread and most effective Russian vaccine against coronavirus today.

Just one injection: what is known about the Sputnik Light coronavirus vaccine

What is "Sputnik Light"

Sputnik Light is a one-component vaccine against coronavirus. Her clinical trials began in January 2021. The main difference between Sputniks is that Sputnik Light is entered only once. In fact, this is the first component of the two that make up the "big" Sputnik.

The single-component Sputnik was registered on May 6, 2021 and became the world's second single-component vaccine after the drug from Johnson & Johnson, registered a few months earlier.

What is a single-dose vaccine for?

Initially, it was assumed that Sputnik Light will become an exclusively export option and will be sent to countries where there are no own vaccines, and the incidence is high. Using a single-dose vaccine will help slow the spread of the virus, at least slightly, reduce the incidence of illness, and save the lives of people at risk of getting sick.

However, later there was evidence that it would be introduced into civil circulation in our country. Now it is used to vaccinate foreigners working in Russia, as well as to vaccinate those who have already had a coronavirus infection, but have a low level of antibodies. In addition, the drug can be used for revaccination. In those who already had immunity, the increase in antibody levels will begin 10 days after vaccination.

Immediately after the registration of the drug, Deputy Prime Minister Tatyana Golikova said that Sputnik Light is intended for people aged 18 to 60 years.

What does Sputnik Light protect from?

According to preliminary estimates, the effectiveness of Sputnik Light is about 80%, which is slightly lower than the effectiveness of Sputnik V (97.6%). However, this figure is higher than that of some released two-component vaccines, such as the AstraZeneca vaccine, which is estimated to be 80% effective. Maximum protection after vaccination can be expected after 28 days.

You can be vaccinated with "Sputnik Light" if you have not been vaccinated and have not been sick

Despite the fact that Sputnik Light is the first component of the Sputnik V vaccine, experts recommend that those who are vaccinated for the first time follow the standard scheme and be vaccinated in two stages with an interval of 21 days. This approach will provide maximum protection.

However, one dose is better than nothing at all. In clinical studies, scientists have found that even those who received just one dose of Sputnik V fell ill less often than those who received a placebo, that is, who were not given the vaccine at all.

Sputnik Light will not replace Sputnik V, but will be used in parallel with it. These vaccines serve different purposes. "Sputnik V" is intended for primary vaccination, for those who have not yet been vaccinated with any drugs and have not been ill with covid, and Sputnik Light is more suitable for revaccination of those who have already been ill or those who have been vaccinated for a long time. In addition, it can be used in emergencies when there are no vaccines available and the population needs to be protected.

When do I need to get vaccinated against coronavirus again?

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There are no clear rules regulating at what level of antibodies revaccination is necessary. This issue is only being investigated. But existing data indicate that it is worth re-vaccinating those who were vaccinated (or had been ill) more than six months ago.

To understand exactly when to re-vaccinate, you need to find out how long immunity lasts after illness and after vaccination.This requires long-term observation of a large number of vaccinated. Such observations are being conducted now, and data are being collected for each of the vaccines existing in the world. So far, the evidence suggests that the vaccine protects for at least six months, but it is possible that it works longer.

How to vaccinate against covid in Russia?

There are currently four vaccines in circulation. In addition to Sputnik Light, it is also Sputnik V, also known as GamKovidVak, publications about which are posted on the pages of the most authoritative scientific journals.

In addition, the domestic Ministry of Health has authorized the use of EpiVacCorona and Kovivac preparations, created in various Russian research organizations, for mass vaccination.

All of these vaccines work differently. "EpiVacCorona" is a peptide vaccine, the details of which the manufacturer is reluctant to give. Kovivac is an inactivated virus vaccine that is arguably the most widely used vaccine approach.

Most of the evidence of how the vaccine works, what side effects it causes, how antibodies are formed, is in the Sputnik V preparation, a vaccine that is recognized in 60 countries around the world. Data on the use of this vaccine are also of foreign origin - in Argentina, where they are also vaccinated with Sputnik, the effectiveness of the drug was estimated at 79%.

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